DNA Testing

DNA or Gene Testing is an individual approach in order to improve weight loss by means of following the right diet according to your gene-set. Improving your health by means of supporting bodily systems that may be weak and needs lifestyle support. In this way preventing disease in the longterm and also being aware of your potential disease risks. Looking at prevention of lifestyle related cancers i.e. breast and ovarian cancers and optimising your sports performance by means of ascertaining your muscle fibre type, injury risk and recovery rates. Wonderful isn’t it? This is the technology of the future based on your own body and what it needs to be thin, healthy and athletic.

We offer DNA testing at the practice and do the test and courier it to the lab on your behalf. We do not deal with the payments which is done directly to the DNA lab. We will however assist you in any way needed.

Test results can take anything from 2 – 4 weeks. If you would like to do a tests, you can contact the practice and we will arrange for a sample to be taken either at our offices or send the test kit to your home. The sample is a simple mouth swab and easy and painless to do. Your results will take three weeks to be released and the reports are sent directly to us and will be uploaded to your profile.

DNA Testing Procedure

.


DNA DIET

One of the first products of its kind in the world, DNA Diet is designed to assist the healthcare practitioner in the design of a personalised healthy eating plan based on individual genetic differences.

DNA Diet also provides additional insight into how each individual reacts to carbohydrates, saturated fats and intensity of exercise, allowing your dietician to further personalise your eating plan to suit your needs

Let’s look at how your genes can impact your weight. Obesity is a complex disease which results from not only genetic factors but is triggered by your environment. Many individuals may have a genetic predisposition that may lead to obesity. The genes involved here are genes that interact with environmental factors like the type of foods you consume in your diet as well as your activity levels.

For instance: you come from an overweight family. You probably have the genetic potential to put on weight too. You however, exercise frequently, avoid unhealthy foods and use nutritional supplementation to control your appetite. You are the only person in your family that is of a normal weight. Your sister on the other hand was born with a dislike in physical movement, a love for sugar and spice and really struggles to control her dietary intake.  She has therefore given up the battle of the bulge as nothing she endeavours seems to last or help control her weight problem.

Sequence variations within a pool of 56 different genes have been reported as being related to obesity. Identification of these genes (DNA DIET TEST) will help clarify the reason that you are struggling with your weight. A few genes to mention that can affect weight loss are:

  • Increased appetite (Yes this can be genetic, gene FTO, MC4R, TCF7L2)
  • A constant craving for sweet things (Yes this too is genetic TAS1R2)
  • Insulin Resistance (ARDB2 Gln27Glu, FABP2)
  • Saturated fat sensitivity (FABP2, ARDB2, APOA5)
  • Your bodies resistance to weight loss (Gene ARDB3, PLIN)
  • Reduced ability to mobilise fat from fat stores (Gene ARDB2 arg16gly)

By having your gene screen done (DNA Diet – we collect the test sample at the Practice or it is sent to you via Courier directly to you home with full instructions), you will have a very clear idea and understanding as to where your focus should be with your weight loss strategy. Whether it is to take something natural for appetite control, or to reduce the saturated fat or carbohydrate intake in your diet, using L-Carnitine based products can assist with the breakdown of fat in your body.  And there is plenty more products available to assist.

The tests will also identify patients who are at risk of gaining weight. You might want to consider screening your kids if both parents are overweight, or doing the test if your child struggles with his/her weight. Implementing good lifestyle habits when kids are young is much more successful in managing weight than trying to change habits when you are older.

Give this one a go, it worked for me……


DNA HEALTH

An extract of one of the Panels in the DNA Health Test

The DNA Health test is designed to optimise wellbeing and health by personalising lifestyle and diet choices and, where necessary, using supplements tailored to offset any particular nutritional deficit based on specific gene variants. The DNA Health in a nutshell will identify genetically weaker areas in your body which could be related to some symptoms that you may experience i.e. Bloating, Food intolerances, Fatigue, Depression, Hormone Imbalances, Joint and body pains etc. These symptoms could be easily rectified if a practitioner knows where the cause lies. With DNA Health one can identify root causes of symptoms and prevent lifestyle diseases by means of knowing where the problem areas lie and changing your diet and lifestyle accordingly.

We test for 36 gene variants to identify any precursors to lifestyle diseases such as:

Cholesterol metabolism and risk for heart disease | Bone Health & risk for osteoporosis | Methylation and B Vitamin requirements | Detoxification| Inflammation and oxidative stress | Insulin Sensitivity and risk for diabetes | Food Responsiveness i.e. lactose intolerance, gluten intolerance, caffeine processing, salt sensitivity, blood pressure and iron overload disorders | Vitamin and Nutrient metabolism


DNA ESTROGEN

80% of breast cancer occurs in women with no family history. Oestrogen gene testing may help you lessen your risk of undetected cancers. Research has shown that an increased lifetime exposure to oestrogen is a strong risk factor in the development of breast cancer.

DNA Oestrogen tests for gene variants that have been shown to have an impact on how oestrogen is processed in your body and if the processing of oestrogen and related compounds is efficient. The DNA Estrogen tests will also help to identify if you are at risk of hormone imbalances and could also explain why you may suffer with Polycystic ovaries, infertility, Pre-menstrual stress and many more problems related to hormones.

Not only does DNA Oestrogen benefit men and women who suffer from numerous oestrogen-dominant conditions, but the test is particularly important for woman considering:

  • oral contraceptives,
  • hormone replacement therapy,
  • bio-identical supplementation,
  • in-vitro fertilisation, or
  • who have been diagnosed with oestrogen receptor-positive breast cancer.

DNA Oestrogen reports on the following areas:

  • Variations in key genes involved in metabolizing oestrogen and related compounds
  • Intervention strategies for carriers of high-risk genetic variations
  • Personal risk factors associated with HRT, Oral contraceptives, bio-identical supplementation and in vitro fertilization

The DNA Oestrogen test guides the personalisation of diet, hormone and nutritional supplement recommendations to improve oestrogen metabolism.


DNA SPORT

DNA Sport examines various biological areas that impact training responsiveness and sporting performance. These include soft tissue remodeling, inflammation, blood flow and respiration, energy production and fuel metabolism.

Athletic success results firstly from personalising a training strategy that optimises your genetic potential, and secondly choosing the right lifestyle, nutrition and environmental interactions to optimally express your inherited genes.

The effectiveness of training and sporting performance is affected by key biological areas, and with DNA Sport, we can help personalise a training strategy that optimises your genetic potential, and identify the right lifestyle, nutrition and environmental interactions to optimally express your genetic potential.

Ultimately, DNA Sport can determine the best way to maximise sporting potential, prevent injury and optimise recovery to reach peak levels of conditioning.

DNA Sport reports on the following areas:

  • Structural integrity of soft tissues
  • Inflammation & oxidative stress
  • Blood flow & respiration
  • Energy during exercise
  • Fuel during exercise
  • Caffeine metabolism
  • Muscle and bone composition
  • Aerobic capacity
  • Power/strength potential


DNA MIND

A sound mind in a sound body

According to research, neuropsychiatric disorders account for up to 25% of all disability-adjusted life years. Whilst the heritability of these mental disorders is significant, environmental factors also factor into their development. Genetic variations involved in key biological processes that contribute toward the risk of development of mental health disorders may give insights to the prevention, diagnosis and treatment of the disease.

By understanding an individual’s unique genetic makeup and predispositions, healthcare clinical professionals can better in developing strategies for individuals suffering from, or at risk of, mental health disorders.


The DNA Mind Report Provides:

  • Identification of the level of impact of any genetic variants
  • An explanation of their impact on the specific biochemical area
  • An explanation of each area’s impact on mental health

Taking the test may help you, and/or your patients, understand ways that may avoid the onset of a range of neurological disorders.

The DNA Mind test analyses 30 genes which have been shown to have significant associations with key mental health disorders, and reports on the following areas:

Neurodegenerative disorders

Alzheimer’s disease, dementia, cognitive decline

Addictive behaviour

  • A risk for alcohol, nicotine, cannabis & opioid dependence; Psychosis response from cannabis use; eating disorders (binge eating)

Adrenaline-seeking

  • Risk-taking behaviour

Mood disorders

  • Depression, bipolar, anxiety and post-traumatic stress


DNA SKIN

Firmness and elasticity
Sun sensitivity & pigmentation
Sun damage, protection & repair
Antioxidant status
Inflammation

Look younger for longer with a healthier skin

Your genetics determines everything about you, including how your DNA handles the potentially destructive exposure to UV rays. Based on the results from the DNA Skin test, personalised lifestyle, nutrition, nutraceutical and cosmeceutical recommendations can be given for improved skin care and to decrease the visible signs of ageing.

We can help you identify potential risk factors and inherent propensities to a range of skin conditions and qualities, from oily skin to freckling.

DNA Skin tests for 19 gene variations involved in the following areas;

  • Firmness and elasticity
  • Sun sensitivity & pigmentation
  • Sun damage, protection & repair
  • Antioxidant status
  • Inflammation

We recommend personalised lifestyle, nutrition, nutraceutical and cosmeceutical choices for improved skin care and to decrease the visible signs of ageing.


DNA GrowBaby

GrowBaby is a genetic test for mom-to-be, designed to help you better understand the functioning of key biological pathways that influence maternal and fetal health, and how these relate to the major birth phenotypes.

The report provides valuable insights into how you can optimise health outcomes for mom and baby using gene-based personalised diet, supplement, and lifestyle interventions.

DNA Growbaby identifies maternal and fetal risks which can be prevented by the correct diet and supplement regime.

Preconception and the perinatal time period provide a unique opportunity to establish the foundations for optimum health and development across the lifespan. Targeted interventions, using insights from a genetic test, can optimise the health of the mother, supporting a healthier pregnancy, and resulting in transgenerational health and resilience.


DNA SMILE

Evidence shows that certain gene variants have been implicated in the pathogenesis of periodontal disease

DNA Smile analyses 22 SNPs in 16 genes involved in 5 key biological processes associated with oral health outcomes

These variants have been linked to an altered immune and inflammatory response to pathogenic bacteria in the mouth, leading to increased risk for periodontitis

Insight into these areas assists with the targeted management of oral health and decreasing the risk for related chronic disease.


DNA MEDCHECK

Medcheck is a pharmacogenomics tests that look at how you respond to specific medications such as Pain medication, Anti-depressants, Cholesterol medications, Beta Blockers, anti-coagulants and more. This test is ideal for when you are prescribed a new drug treatment and not sure how your body will respond. The test would be able to indicate potential reduce efficacy, increased toxicity for certain drugs. Along with this information suggested altered dosing instructions will be provided. If there is no genes that interact with certain medications, the medication can be prescribed at the normal dosing instruction.

A good example is for instance when a doctor prescribes and anti-depressant to a patient. Without knowing the information provided in this test, this patient experienced significant weight gain due to the use of this specific anti-depressant. If the patient had known that those class of antidepressants would cause significant weight gain, they could have chosen a different drug altogether.